| | | Wednesday, October 12th, 2011 | | Activated RF T. Holmes from the disabled list. |
| Thursday, October 6th, 2011 | | Activated 1B K. Bransfield from the disabled list. |
| Thursday, September 22nd, 2011 | | Placed SP J. Beckett on the 60-day disabled list. | | Placed RF T. Holmes on the 15-day disabled list. |
| Saturday, September 17th, 2011 | | Activated C R. Schalk from the disabled list. |
| Friday, September 16th, 2011 | | Placed 1B K. Bransfield on the 15-day disabled list. |
| Wednesday, September 7th, 2011 | | Placed LF C. Hart on the 15-day disabled list. | | Activated 2B M. Kata from the disabled list. | | Signed free agent SS J. Peters to a minor league contract. |
| Tuesday, August 30th, 2011 | | Placed C R. Schalk on the 15-day disabled list. |
| Monday, August 29th, 2011 | | Activated 2B L. Pike from the 60-day disabled list. |
| Wednesday, August 3rd, 2011 | | Placed 2B M. Kata on the 15-day disabled list. |
| Tuesday, August 2nd, 2011 | | Released MR B. Halsey. |
| Monday, August 1st, 2011 | | Signed free agent MR K. Sasaki to a minor league contract. |
| Friday, July 15th, 2011 | | Signed free agent SS B. Zobrist to a minor league contract. |
| Thursday, July 7th, 2011 | | Activated SS G. Johnson from the disabled list. |
| Thursday, June 30th, 2011 | | Signed free agent MR S. McMahon to a minor league contract. |
| Thursday, June 23rd, 2011 | | Placed LF A. Oms on the 60-day disabled list. |
| Saturday, June 11th, 2011 | | Activated 2B B. Hallman from the disabled list. |
| Friday, June 10th, 2011 | | Placed SS G. Johnson on the 15-day disabled list. |
| Monday, May 30th, 2011 | | Placed 2B L. Pike on the 60-day disabled list. |
| Friday, May 27th, 2011 | | Placed 2B B. Hallman on the 15-day disabled list. |
| Thursday, May 19th, 2011 | | Activated CF T. Holmes from the disabled list. |
| Thursday, May 12th, 2011 | | Activated CF W. Taveras from the disabled list. |
| Sunday, May 1st, 2011 | | Placed CF T. Holmes on the 15-day disabled list. |
| Monday, April 25th, 2011 | | Placed CF W. Taveras on the 15-day disabled list. |
| Tuesday, March 29th, 2011 | | Activated 2B A. Callaspo from the disabled list. |
| Monday, March 14th, 2011 | | Placed 2B A. Callaspo on the 15-day disabled list. |
| Friday, January 21st, 2011 | | Released MR D. Turnbow. |
| Thursday, January 20th, 2011 | | Signed free agent MR D. Turnbow to a minor league contract. |
| Wednesday, November 17th, 2010 | | Released MR D. Turnbow. |
| Monday, November 15th, 2010 | | Drafted RF T. Holmes in the 2010 first-year player draft (Round 1, Pick 4, 4th overall Pick). | | Drafted MR A. Brazle in the 2010 first-year player draft (Round 2, Pick 4, 20th overall Pick). | | Drafted MR R. Scarborough in the 2010 first-year player draft (Round 3, Pick 4, 36th overall Pick). | | Drafted SP B. Lemon in the 2010 first-year player draft (Round 4, Pick 4, 52nd overall Pick). | | Drafted CF S. Spence in the 2010 first-year player draft (Round 5, Pick 4, 68th overall Pick). |
| Monday, November 8th, 2010 | | SP T. Bond received a 1-year contract through automatic renewal worth a total of $131,565. | | 3B G. Johnson received a 1-year contract through automatic renewal worth a total of $131,565. | | RF J. Ryan received a 1-year contract through automatic renewal worth a total of $131,565. | | SP C. Sweeney received a 1-year contract through automatic renewal worth a total of $131,565. | | CF C. Figgins received a 1-year contract through automatic renewal worth a total of $131,565. | | MR J. Beckett received a 1-year contract through automatic renewal worth a total of $131,565. | | SP J. Meekin received a 1-year contract through automatic renewal worth a total of $131,565. | | RF C. Hart received a 1-year contract through automatic renewal worth a total of $131,565. | | CL S. Stewart received a 1-year contract through automatic renewal worth a total of $131,565. | | SP J. Cruz received a 1-year contract through automatic renewal worth a total of $131,565. | | LF A. Oms received a 1-year contract through automatic renewal worth a total of $131,565. | | SP A. Sonnanstine received a 1-year contract through automatic renewal worth a total of $131,565. | | MR C. Zambrano received a 1-year contract through automatic renewal worth a total of $131,565. | | MR J. Verlander received a 1-year contract through automatic renewal worth a total of $131,565. | | C E. McFarland received a 1-year contract through automatic renewal worth a total of $131,565. | | SS J. Uribe received a 1-year contract through automatic renewal worth a total of $131,565. | | SS A. Berroa received a 1-year contract through automatic renewal worth a total of $131,565. | | 1B K. Bransfield received a 1-year contract through automatic renewal worth a total of $131,565. | | CF W. Taveras received a 1-year contract through automatic renewal worth a total of $131,565. | | LF J. Tyner received a 1-year contract through automatic renewal worth a total of $131,565. | | 2B B. Hallman received a 1-year contract through automatic renewal worth a total of $131,565. | | 2B L. Pike received a 1-year contract through automatic renewal worth a total of $131,565. | | CF M. Carey received a 1-year contract through automatic renewal worth a total of $131,565. | | MR A. Mamaux received a 1-year contract through automatic renewal worth a total of $131,565. | | C R. Schalk received a 1-year contract through automatic renewal worth a total of $131,565. |
| Saturday, November 6th, 2010 | | Signed team doctor M. Ramírez to a 5-year, $85,000 per year contract. |
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