| | | Thursday, September 15th, 2011 | | Placed 2B D. Johnson on the 15-day disabled list. |
| Wednesday, August 24th, 2011 | | Activated 2B S. Bankhead from the disabled list. | | Released 3B S. White. |
| Sunday, August 14th, 2011 | | Activated SP C. Hamels from the 60-day disabled list. |
| Tuesday, August 9th, 2011 | | Placed 2B S. Bankhead on the 15-day disabled list. |
| Thursday, August 4th, 2011 | | Activated MR G. Mogridge from the 60-day disabled list. | | Released SS J. Peters. |
| Friday, July 1st, 2011 | | Activated MR W. Cooper from the disabled list. |
| Sunday, June 12th, 2011 | | Activated C A. Robinson from the disabled list. |
| Saturday, May 28th, 2011 | | Placed C A. Robinson on the 15-day disabled list. |
| Thursday, May 19th, 2011 | | Placed MR W. Cooper on the 15-day disabled list. |
| Sunday, May 15th, 2011 | | Activated C B. McCann from the disabled list. |
| Thursday, May 12th, 2011 | | Placed SP C. Hamels on the 60-day disabled list. |
| Monday, April 25th, 2011 | | Signed free agent SS J. Peters to a minor league contract. |
| Thursday, April 14th, 2011 | | Placed C B. McCann on the 15-day disabled list. |
| Monday, April 4th, 2011 | | Released LF J. Bay. | | Signed free agent MR B. Medders to a minor league contract. | | Released MR J. Devlin. |
| Wednesday, March 16th, 2011 | | Placed MR G. Mogridge on the 60-day disabled list. | | Activated 1B T. Hafner from the 60-day disabled list. |
| Sunday, March 6th, 2011 | | Signed free agent MR C. Vargas to a 1-year contract worth a total of $131,565. |
| Sunday, February 13th, 2011 | | Signed free agent MR W. McDonald to a 1-year contract worth a total of $180,000. | | Released 1B J. Daubert. |
| Tuesday, January 25th, 2011 | | Released MR D. Turnbow. |
| Monday, January 24th, 2011 | | Signed free agent MR D. Turnbow to a minor league contract. |
| Saturday, January 15th, 2011 | | Released MR D. Turnbow. |
| Friday, January 14th, 2011 | | Signed free agent MR D. Turnbow to a minor league contract. |
| Wednesday, January 12th, 2011 | | Signed free agent MR G. Mogridge to a 1-year contract worth a total of $230,000. | | Released 2B K. Gleason. |
| Saturday, January 8th, 2011 | | Released MR D. Turnbow. |
| Friday, January 7th, 2011 | | Signed free agent MR D. Turnbow to a minor league contract. |
| Thursday, January 6th, 2011 | | Released MR D. Turnbow. |
| Wednesday, January 5th, 2011 | | Signed free agent MR D. Turnbow to a minor league contract. |
| Tuesday, January 4th, 2011 | | Signed free agent MR N. Altrock to a 1-year contract worth a total of $185,000. | | Released MR D. Turnbow. |
| Saturday, December 25th, 2010 | | Signed free agent MR E. Morris to a 2-year contract worth a total of $750,000. | | Released MR G. Hecker. |
| Wednesday, November 24th, 2010 | | Activated CL G. Hecker from the 60-day disabled list. | | Released 3B J. Collins. |
| Friday, November 19th, 2010 | | Released RF E. Daily. |
| Thursday, November 18th, 2010 | | Signed free agent MR D. Turnbow to a minor league contract. |
| Monday, November 15th, 2010 | | Drafted CF H. Walker in the 2010 first-year player draft (Round 1, Pick 6, 6th overall Pick). | | Drafted LF H. Sauer in the 2010 first-year player draft (Round 2, Pick 6, 22nd overall Pick). | | Drafted C A. Robinson in the 2010 first-year player draft (Round 3, Pick 6, 38th overall Pick). | | Drafted RF A. Zarilla in the 2010 first-year player draft (Round 4, Pick 6, 54th overall Pick). | | Drafted 2B D. Johnson in the 2010 first-year player draft (Round 5, Pick 6, 70th overall Pick). |
| Monday, November 8th, 2010 | | LF G. Hall received a 1-year contract through automatic renewal worth a total of $131,565. | | MR J. Devlin received a 1-year contract through automatic renewal worth a total of $131,565. | | CF G. Beaumont received a 1-year contract through automatic renewal worth a total of $131,565. | | CL G. Hecker received a 1-year contract through automatic renewal worth a total of $131,565. | | RF S. Seybold received a 1-year contract through automatic renewal worth a total of $131,565. | | SP C. Hamels received a 1-year contract through automatic renewal worth a total of $131,565. | | CL B. Lidge received a 1-year contract through automatic renewal worth a total of $131,565. | | C B. McCann received a 1-year contract through automatic renewal worth a total of $131,565. | | MR C. Marmol received a 1-year contract through automatic renewal worth a total of $131,565. | | LF J. Bay received a 1-year contract through automatic renewal worth a total of $131,565. | | 1B T. Hafner received a 1-year contract through automatic renewal worth a total of $131,565. | | 1B A. LaRoche received a 1-year contract through automatic renewal worth a total of $131,565. | | C J. Closser received a 1-year contract through automatic renewal worth a total of $131,565. | | LF S. Mertes received a 1-year contract through automatic renewal worth a total of $131,565. | | 2B M. Ensberg received a 1-year contract through automatic renewal worth a total of $131,565. | | 1B L. Overbay received a 1-year contract through automatic renewal worth a total of $131,565. | | CF C. Sullivan received a 1-year contract through automatic renewal worth a total of $131,565. | | SP A. Eaton received a 1-year contract through automatic renewal worth a total of $131,565. | | 1B J. Start received a 1-year contract through automatic renewal worth a total of $131,565. | | SP J. Duryea received a 1-year contract through automatic renewal worth a total of $131,565. | | 3B S. White received a 1-year contract through automatic renewal worth a total of $131,565. | | SS R. Chapman received a 1-year contract through automatic renewal worth a total of $131,565. | | SP B. Shawkey received a 1-year contract through automatic renewal worth a total of $131,565. | | MR W. Cooper received a 1-year contract through automatic renewal worth a total of $131,565. |
| Wednesday, October 20th, 2010 | | Activated CF C. Sullivan from the disabled list. |
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